Smoking and Fatal Prostate Cancer in a Large Cohort of Adult Men

摘要: The authors examined the relation between smoking and risk of fatal prostate cancer in a large prospective mortality study 450,279 men who were free at enrollment 1982. During 9 years follow-up, 1,748 deaths occurred from cancer. Cox proportional hazards modeling was used to adjust for other factors. Current cigarette associated with (rate ratio = 1.34, 95% confidence interval (CI) 1.16-1.56). rate greater younger ages, decreasing 1.83 (95% CI 1.04-3.24) among below age 60 1.11 0.79-1.58) aged 80 above (p trend 0.16). No observed number cigarettes per day or duration current smokers baseline, no increased found former smokers. Race did not significantly modify association These data, together those three studies that find higher death rates smokers, inconsistent findings incidence suggest may adversely affect survival patients.