EEG slow waves and sleep spindles: windows on the sleeping brain

摘要: Slow waves and sleep spindles are prominent features of the EEG in non-REM some neurophysiological mechanisms underlying their genesis have been elucidated. In humans, slow-wave activity increases frequency range decreases when wakefulness prior to is varied from 2 40 h. The opposite changes observed course sleep, even scheduled out phase with circadian rhythm propensity. Within episodes association between slow bi-phasic: both activities correlated positively at beginning end whereas middle part high values coincide low levels spindle activity. An extension enhances rise rate onset sleep. Since macroscopic dependent on hyperpolarization synchronization neurons thalamo-cortical cortical circuits, deprivation induced these may be related reduced activating input neurons, local facilitation or synchronization. precise regulation as a function duration intensity demonstrates that oscillations accurate indicators non-REM-sleep homeostasis suggests they fundamental sleeping brain.