The Fertilization Calcium Signal and How it is Triggered

摘要: Publisher Summary This chapter describes how the calcium transient is detonated by sperm, it spreads so rapidly through egg, and that a increase in Ca i leads to progression into cell cycle. It turns out waves of sort were first seen eggs are general property signaling systems somatic cells too. Calcium have built them positive feedback mechanisms give rise spatial temporal oscillations free concentration when system stimulated fixed amount external agonist. The two sides same coin. unifying feature they primarily involve modulated release reuptake from intracellular stores. site resequestration generally accepted be endoplasmic reticulum. Eggs provide beautiful examples oscillations. Hamster experience both at fertilization. multiple transients after fertilization hamster can reproduced with varying degrees fidelity artificial activating agents.