Investigation of U-251 cell death triggered by flavonoid luteolin: towards a better understanding on its anticancer property against glioblastomas.

作者: Yollanda E. M. Franco , Carolina A. de Lima , Marcela N. Rosa , Viviane A. O. Silva , Rui M. Reis

DOI: 10.1080/14786419.2020.1727470

关键词:

摘要: Recently, many studies have reported the anticancer properties of flavonoid luteolin against a variety tumors, but there is still lack in description its mechanism action. In attempt...

参考文章(27)
Jiuan-Jiuan Hwang, Madhavan P Nair, Ping-Ping H Lee, Ferng-Chun Ke, Lung-Ta Lee, Chithan Kanadaswam, Ming-Ting Lee, Ying-Tang Huang, Blockade of the epidermal growth factor receptor tyrosine kinase activity by quercetin and luteolin leads to growth inhibition and apoptosis of pancreatic tumor cells. Anticancer Research. ,vol. 22, pp. 1615- 1627 ,(2002)
Cláudia Q da Rocha, Fabiana C Vilela, Flávia V Santa-Cecília, Gustavo P Cavalcante, Wagner Vilegas, Alexandre Giusti-Paiva, Marcelo H dos Santos, None, Oleanane-type triterpenoid: an anti-inflammatory compound of the roots Arrabidaea brachypoda Revista Brasileira De Farmacognosia-brazilian Journal of Pharmacognosy. ,vol. 25, pp. 228- 232 ,(2015) , 10.1016/J.BJP.2015.03.005
Linlin Lv, Lingli Zheng, Deshi Dong, Lina Xu, Lianhong Yin, Youwei Xu, Yan Qi, Xu Han, Jinyong Peng, Dioscin, a natural steroid saponin, induces apoptosis and DNA damage through reactive oxygen species: a potential new drug for treatment of glioblastoma multiforme Food and Chemical Toxicology. ,vol. 59, pp. 657- 669 ,(2013) , 10.1016/J.FCT.2013.07.012
Prema S. Rao, Arun Satelli, Majid Moridani, Marjorie Jenkins, U. Subrahmanyeswara Rao, Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: involvement of cell line-specific apoptotic mechanisms International Journal of Cancer. ,vol. 130, pp. 2703- 2714 ,(2012) , 10.1002/IJC.26308
Shyang-guang Wang, Ming-hung Huang, Jui-hsiang Li, Fu-i Lai, Horng-mo Lee, Yuan-nian Hsu, Punicalagin induces apoptotic and autophagic cell death in human U87MG glioma cells. Acta Pharmacologica Sinica. ,vol. 34, pp. 1411- 1419 ,(2013) , 10.1038/APS.2013.98
Marcel Karabin, Tereza Hudcova, Lukas Jelinek, Pavel Dostalek, Biotransformations and biological activities of hop flavonoids. Biotechnology Advances. ,vol. 33, pp. 1063- 1090 ,(2015) , 10.1016/J.BIOTECHADV.2015.02.009
Hong-Chao Pan, Qiong Jiang, Yang Yu, Jin-Ping Mei, Yu-Kun Cui, Wei-Jiang Zhao, Quercetin promotes cell apoptosis and inhibits the expression of MMP-9 and fibronectin via the AKT and ERK signalling pathways in human glioma cells. Neurochemistry International. ,vol. 80, pp. 60- 71 ,(2015) , 10.1016/J.NEUINT.2014.12.001
Divyashree Ravishankar, Amit Kumar Rajora, Francesca Greco, Helen. M.I. Osborn, Flavonoids as prospective compounds for anti-cancer therapy The International Journal of Biochemistry & Cell Biology. ,vol. 45, pp. 2821- 2831 ,(2013) , 10.1016/J.BIOCEL.2013.10.004
Michalis Fragkos, Jaana Jurvansuu, Peter Beard, H2AX Is Required for Cell Cycle Arrest via the p53/p21 Pathway Molecular and Cellular Biology. ,vol. 29, pp. 2828- 2840 ,(2009) , 10.1128/MCB.01830-08
Conor M. Henry, Emilie Hollville, Seamus J. Martin, Measuring apoptosis by microscopy and flow cytometry Methods. ,vol. 61, pp. 90- 97 ,(2013) , 10.1016/J.YMETH.2013.01.008