Effect of coronary angioplasty on electrocardiographic changes in patients with unstable angina secondary to left anterior descending coronary artery disease.

摘要: The effect of semiemergent percutaneous transluminal coronary angioplasty on clinical and electrocardiographic (ECG) variables was assessed in 76 patients with unstable angina secondary to an isolated severe proximal left anterior descending artery stenosis. All manifested symmetric T wave inversion two or more ECG leads. Wall motion abnormalities were present 37 ventriculography before dilation. Angioplasty successful 70 (92%), resulting a reduction luminal diameter stenosis from 91 +/- 8% 21 6%, no major acute procedure-related complications observed. other six underwent semiurgent (less than 48 h) bypass surgery three experienced myocardial infarction (before two). Serial ECGs revealed complete resolution ST-T changes 51% at 14 weeks 90% 28 weeks. In contrast, prolongation the corrected QT interval, which 16 (8%), normalized within h angioplasty. Twelve these prolonged interval had nonocclusive thrombus formation poor collateral circulation angiography. Patients followed up for 6 43 months (mean 23 10). Angiographic evidence restenosis 34% patients, all whom second third procedure. One death occurred 8 after completely resolved 13 15 who repeat ventriculography, time 10 normal ECG. This study demonstrates that may persist 7 undergo disease angina. Semiemergent associated high initial success rate excellent long-term outcome.