variancePartition: Interpreting drivers of variation in complex gene expression studies

作者: Gabriel E Hoffman , Eric E Schadt

DOI: 10.1101/040170

关键词:

摘要: As genomics studies become more complex and consider multiple sources of biological technical variation, characterizing these drivers variation becomes essential to understanding disease biology regulatory genetics. We describe a statistical visualization framework, variancePartition, prioritize with genome-wide summary, identify genes that deviate from the trend. variancePartition enables rapid interpretation gene expression is applicable many assays.

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