Using truncated guide rnas (tru-grnas) to increase specificity for rna-guided genome editing

作者: J. Keith Joung , Morgan Maeder , Jeffry D. Sander , Yanfang Fu

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摘要: Methods for increasing specificity of RNA-guided genome editing, e.g., editing using CRISPR/Cas9 systems, truncated guide RNAs (tru-gRNAs).

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