Scn9a antisense oligonucleotides

作者: Kangwon Jang , Heungsik Yoon , Bongjun Cho , Shin Chung , Daram Jung

DOI:

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摘要: The current invention provides peptide nucleic acid derivatives targeting a part of the human SCN9A pre-mRNA. potently induce splice variants mRNA in cells, and are useful to safely treat pains or conditions involving Na v 1.7 activity.

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