The inflammatory response to ischemic acute kidney injury: a result of the 'right stuff' in the 'wrong place'?
作者： Christopher Y Lu , John Hartono , Martin Senitko , Jianlin Chen
DOI: 10.1097/MNH.0B013E3280403C4E
关键词:
摘要: Purpose of review Ischemic acute kidney injury may be exacerbated by an inflammatory response. How elicits inflammation remains a major question in understanding injury. The present examines the hypothesis that molecules released injured cells elicit inflammation. Recent findings After necrotic death, intracellular find their way into extracellular space. These include heat shock proteins and HMGB1. Receptors for these TLR4, TLR2, CD91 RAGE. proinflammatory mechanisms so useful nature has evolved programming death via poly(ADP-ribose) polymerase cyclophilin D. In addition, apoptosis also Summary concepts discussed this are important clinical medicine. Drugs genetic manipulation ameliorate ischemic regulating response to cell
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Tetsuro Shishido, Naoki Nozaki, Seiji Yamaguchi, Yoko Shibata, Joji Nitobe, Takuya Miyamoto, Hiroki Takahashi, Takanori Arimoto, Kunihiko Maeda, Mitsunori Yamakawa, Osamu Takeuchi, Shizuo Akira, Yasuchika Takeishi, Isao Kubota, Toll-Like Receptor-2 Modulates Ventricular Remodeling After Myocardial Infarction Circulation. ,vol. 108, pp. 2905- 2910 ,(2003) , 10.1161/01.CIR.0000101921.93016.1C
Pierce Park, Mark Haas, Patrick N. Cunningham, Lihua Bao, Jessy J. Alexander, Richard J. Quigg, Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes. American Journal of Physiology-renal Physiology. ,vol. 282, ,(2002) , 10.1152/AJPRENAL.00160.2001
Katherine A. Barsness, John Arcaroli, Alden H. Harken, Edward Abraham, Anirban Banerjee, Leonid Reznikov, Robert C. McIntyre, Hemorrhage-induced acute lung injury is TLR-4 dependent American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 287, ,(2004) , 10.1152/AJPREGU.00412.2003
J. Stebbing, All for CD91 and CD91 for all Journal of Antimicrobial Chemotherapy. ,vol. 53, pp. 1- 3 ,(2003) , 10.1093/JAC/DKH010
Maximilian Zeyda, Marcus D. Säemann, Gerhard J. Zlabinger, Thomas Weichhart, Alexander von Gabain, Michael Schunn, Shizuo Akira, Uwe von Ahsen, Thomas M. Stulnig, Walter H. Hörl, Karl M. Stuhlmeier, Yuri Sobanov, Günther Staffler, Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4–dependent mechanism Journal of Clinical Investigation. ,vol. 115, pp. 468- 475 ,(2005) , 10.1172/JCI22720
Aimee L Edinger, Craig B Thompson, Death by design: apoptosis, necrosis and autophagy Current Opinion in Cell Biology. ,vol. 16, pp. 663- 669 ,(2004) , 10.1016/J.CEB.2004.09.011
Ingrid E. Dumitriu, Paramita Baruah, Angelo A. Manfredi, Marco E. Bianchi, Patrizia Rovere-Querini, HMGB1: guiding immunity from within Trends in Immunology. ,vol. 26, pp. 381- 387 ,(2005) , 10.1016/J.IT.2005.04.009
A. Schober, E. Müller, K. Thurau, F. X. Beck, The response of heat shock proteins 25 and 72 to ischaemia in different kidney zones. Pflügers Archiv: European Journal of Physiology. ,vol. 434, pp. 292- 299 ,(1997) , 10.1007/S004240050399
Diego Bogetti, Howard N Sankary, Tomasz M Jarzembowski, Antonio Manzelli, Peter S Knight, James Thielke, Gregorio Chejfec, Scott Cotler, Jose Oberholzer, Giuliano Testa, Enrico Benedetti, Thymoglobulin induction protects liver allografts from ischemia/reperfusion injury Clinical Transplantation. ,vol. 19, pp. 507- 511 ,(2005) , 10.1111/J.1399-0012.2005.00375.X
Marija Cvetanovic, Justin E. Mitchell, Vimal Patel, Benjamin S. Avner, Yan Su, Paul T. van der Saag, Pamela L. Witte, Stefano Fiore, Jerrold S. Levine, David S. Ucker, Specific Recognition of Apoptotic Cells Reveals a Ubiquitous and Unconventional Innate Immunity Journal of Biological Chemistry. ,vol. 281, pp. 20055- 20067 ,(2006) , 10.1074/JBC.M603920200