Statistical Genomics: Linkage, Mapping, and QTL Analysis

摘要: Introduction Forward Introducing Genomics Statistical Related Books Biology in Mendelian Genetics and Cytogenetics Population Quantitative Molecular Exercises to Genome Genetic Markers Statistics Distribution Likelihood Hypothesis Test Estimation Sample Size Determination Summary Single-Locus Models Expected Segregation Ratio Marker Screening Natural Two-Locus I: Controlled Cross Linkage Detection Recombination Frequency Properties Consideration Dominant F2 Progeny Violation of Assumptions Model II: Phase Problem Mixture Self Random Mating III: Using Disequilibrium Transmission Other Based Analysis Grouping Locus Ordering Three-Locus Multiple-Locus Probability Estimated Orders Exercise Multi-Locus Map Function Distance Coverage Density Merging Factors on Gene Pooling QTL Mapping History Example Data Single-Marker Rationale Backcross Single Interval Composite IV: Open-Pollinated Populations Sib-Pair Method V: Power Multiple VI: Future Considerations Problems with Resolution Strategies What are Computer Tools for Genomic PGRI (Plant Research Initiative Resampling Simulation Bibliography Author Index Subject