A Proposed Target Product Profile and Developmental Cascade for New Cryptosporidiosis Treatments.
作者： Christopher D. Huston , Thomas Spangenberg , Jeremy Burrows , Paul Willis , Timothy N. C. Wells
DOI: 10.1371/JOURNAL.PNTD.0003987
关键词:
摘要: … leads for further development and to define essential developmental milestones. In this article, we propose a target product profile (TPP)(Table 1) and testing cascade (Fig 1) that can be …
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A. Clavel, A. C. Arnal, E. C. Sánchez, F. J. Castillo, M. Varea, R. Gómez-Lus, J. Cuesta, S. Letona, J. A. Amiguet, Respiratory cryptosporidiosis: case series and review of the literature. Infection. ,vol. 24, pp. 341- 346 ,(1996) , 10.1007/BF01716076
Ryan C. Murphy, Kayode K. Ojo, Eric T. Larson, Alejandro Castellanos-Gonzalez, B. Gayani K. Perera, Katelyn R. Keyloun, Jessica E. Kim, Janhavi G. Bhandari, Natascha R. Muller, Christophe L. M. J. Verlinde, A. Clinton White, Ethan A. Merritt, Wesley C. Van Voorhis, Dustin J. Maly, Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii ACS Medicinal Chemistry Letters. ,vol. 1, pp. 331- 335 ,(2010) , 10.1021/ML100096T
Dinesh Mondal Dinesh Mondal, Rashidul Haque Rashidul Haque, RB Sack, BD Kirkpatrick, WA, Jr Petri, None, Attribution of Malnutrition to Cause-Specific Diarrheal Illness: Evidence from a Prospective Study of Preschool Children in Mirpur, Dhaka, Bangladesh The American Journal of Tropical Medicine and Hygiene. ,vol. 80, pp. 824- 826 ,(2009) , 10.4269/AJTMH.2009.80.824
Sushil K. Maurya, Deviprasad R. Gollapalli, Shivapriya Kirubakaran, Minjia Zhang, Corey R. Johnson, Nicole N. Benjamin, Lizbeth Hedstrom, Gregory D. Cuny, Triazole inhibitors of Cryptosporidium parvum inosine 5′-monophosphate dehydrogenase Journal of Medicinal Chemistry. ,vol. 52, pp. 4623- 4630 ,(2009) , 10.1021/JM900410U
Suzanne Stroup, Siripong Tongjai, Ndealilia Swai, Athanasia Maro, Gibson Kibiki, Eric R. Houpt, Dual probe DNA capture for sensitive real-time PCR detection of Cryptosporidium and Giardia Molecular and Cellular Probes. ,vol. 26, pp. 104- 106 ,(2012) , 10.1016/J.MCP.2011.12.003
T.L. Ollivett, D.V. Nydam, D.D. Bowman, J.A. Zambriski, M.L. Bellosa, T.C. Linden, T.J. Divers, Effect of nitazoxanide on cryptosporidiosis in experimentally infected neonatal dairy calves Journal of Dairy Science. ,vol. 92, pp. 1643- 1648 ,(2009) , 10.3168/JDS.2008-1474
Rebecca A Dillingham, Aldo A Lima, Richard L Guerrant, None, Cryptosporidiosis: epidemiology and impact Microbes and Infection. ,vol. 4, pp. 1059- 1066 ,(2002) , 10.1016/S1286-4579(02)01630-1
JEREMY N BURROWS, EMILIE BURLOT, BRICE CAMPO, STEPHANIE CHERBUIN, SARAH JEANNERET, DIDIER LEROY, THOMAS SPANGENBERG, DAVID WATERSON, TIMOTHY NC WELLS, PAUL WILLIS, Antimalarial drug discovery – the path towards eradication Parasitology. ,vol. 141, pp. 128- 139 ,(2014) , 10.1017/S0031182013000826
J.-F. Rossignol, H. Hidalgo, M. Feregrino, F. Higuera, W.H. Gomez, J.L. Romero, J. Padierna, A. Geyne, M.S. Ayers, A double-‘blind’ placebo-controlled study of nitazoxanide in the treatment of cryptosporidial diarrhoea in aids patients in Mexico Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 92, pp. 663- 666 ,(1998) , 10.1016/S0035-9203(98)90804-5
Ping Xu, Giovanni Widmer, Yingping Wang, Luiz S. Ozaki, Joao M. Alves, Myrna G. Serrano, Daniela Puiu, Patricio Manque, Donna Akiyoshi, Aaron J. Mackey, William R. Pearson, Paul H. Dear, Alan T. Bankier, Darrell L. Peterson, Mitchell S. Abrahamsen, Vivek Kapur, Saul Tzipori, Gregory A. Buck, The genome of Cryptosporidium hominis Nature. ,vol. 431, pp. 1107- 1112 ,(2004) , 10.1038/NATURE02977