Modified Frontal Leucotomy: A Review of 106 Cases

摘要: The 106 patients originally seen at St. Thomas's Hospital who subsequently had a modified prefrontal leucotomy between the years 1950 and 1957 were followed up for an average period of five years. Fifty-five considerably improved. Twenty-six showed some improvement. Twenty-four unchanged, one was worse. Ninety-two classified into three groups—obsessive compulsive (sixteen patients), "recurrent affective" (forty patients) "single (thirty-six patients). first two groups fared better than group. There no significant association outcome length illness, age operation, symptomatology. Personality changes noted in twenty-eight patients, severe six patients. change not associated with outcome. None whose personalities made them "operative risks" did well after operation. The results are discussed light other studies what is known "natural history" patients' disorders. It concluded that appears to be considerable value certain psychiatric illnesses, but further evaluation operation can best done—perhaps only done—by controlled clinical trials.