Relation of kidney tissue somatomedin-c/insulin-like growth factor i to postnephrectomy renal growth in the rat

作者: ALAN D. STILES , ILENE R. S. SOSENKO , A. JOSEPH D’ERCOLE , BARRY T. SMITH

DOI: 10.1210/ENDO-117-6-2397

关键词:

摘要: In kidney tissue extracts, we observed elevated somatomedin-C (SmC) concentrations in the remaining after nephrectomy compared to those removed at surgery or kidneys from sham-operated animals. hypophysectomized animals, a response of same magnitude, but significantly lowered basal SmC concentrations. neither case did affect levels serum other tissues studied (liver and lung). The increased regenerating kidney, with return baseline within 30 days, along absence suggest local role for this mitogen organ growth. (Endocrinology 117: 2397–2401, 1985)

参考文章(34)
A. JOSEPH D’ERCOLE, JOSEPH R. WILKINS, Affinity Labeled Somatomedin-C-Binding Proteins in Rat Sera* Endocrinology. ,vol. 114, pp. 1141- 1144 ,(1984) , 10.1210/ENDO-114-4-1141
DORIS ROLF, H. L. WHITE, ENDOCRINE INFLUENCES ON RENAL COMPENSATORY HYPERTROPHY1 Endocrinology. ,vol. 53, pp. 436- 440 ,(1953) , 10.1210/ENDO-53-4-436
J.M. Lopez-Novoa, B. Ramos, J.E. Martin-Oar, L. Hernando, Functional Compensatory Changes after Unilateral Nephrectomy in Rats Kidney & Blood Pressure Research. ,vol. 5, pp. 76- 84 ,(1982) , 10.1159/000172842
C. D. Stiles, G. T. Capone, C. D. Scher, H. N. Antoniades, J. J. Van Wyk, W. J. Pledger, Dual control of cell growth by somatomedins and platelet-derived growth factor Proceedings of the National Academy of Sciences of the United States of America. ,vol. 76, pp. 1279- 1283 ,(1979) , 10.1073/PNAS.76.3.1279
W. J. Pledger, C. D. Stiles, H. N. Antoniades, C. D. Scher, An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis Proceedings of the National Academy of Sciences of the United States of America. ,vol. 75, pp. 2839- 2843 ,(1978) , 10.1073/PNAS.75.6.2839
Ronald A. Malt, Compensatory Growth of the Kidney New England Journal of Medicine. ,vol. 280, pp. 1446- 1459 ,(1969) , 10.1056/NEJM196906262802606
K. Nomura, D. Puett, W. E. Nicholson, G. W. Liddle, Partial purification and characterization of a renotropic fraction from ovine pituitaries. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 79, pp. 6675- 6679 ,(1982) , 10.1073/PNAS.79.21.6675
Nobuto Yamamoto, Hiroshi Kanetake, Jun Yamada, In vitro evidence from tissue cultures to prove existence of rabbit and human renotropic growth factor. Kidney International. ,vol. 23, pp. 624- 631 ,(1983) , 10.1038/KI.1983.68
KENNETH C. COPELAND, LOUIS E. UNDERWOOD, JUDSON J. VAN WYK, Induction of Immunoreactive Somatomedin C in Human Serum by Growth Hormone: Dose-Response Relationships and Effect on Chromatographic Profiles* The Journal of Clinical Endocrinology and Metabolism. ,vol. 50, pp. 690- 697 ,(1980) , 10.1210/JCEM-50-4-690