Effect of insulin and adrenergic agonists on glucose transport of porcine adipocytes
作者： K.A. Akanbi , D.C. England , C.Y. Hu
DOI: 10.1016/0742-8413(90)90183-A
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摘要: Abstract 1. Insulin increased basal 2-deoxyglucose uptake in isolated swine adipocytes by 75%. In the absence of insulin, isoproterenol did not inhibit transport. 2. Adenosine deaminase plus or theophylline alone reduced insulin effect 10 and 40%, respectively. Isoproterenol with 2-chloroadenosine on glucose transport activity. 3. was inhibited presence but adenosine deaminase. 4. These results suggest that catecholamines do counter-regulate insulin-stimulated adipocytes.
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sci-hub.se 参考文章(33)
J M Olefsky, Mechanisms of the ability of insulin to activate the glucose-transport system in rat adipocytes. Biochemical Journal. ,vol. 172, pp. 137- 145 ,(1978) , 10.1042/BJ1720137
Russell Hilf, Laurie K. Sorge, Roger J. Gay, Insulin Binding and Glucose Transport International Review of Cytology. ,vol. 72, pp. 147- 202 ,(1981) , 10.1016/S0074-7696(08)61196-1
George F. Cahill, Bernard Leboeuf, Robert B. Flinn, Studies on rat adipose tissue in vitro. VI. Effect of epinephrine on glucose metabolism. Journal of Biological Chemistry. ,vol. 235, pp. 1246- 1250 ,(1960) , 10.1016/S0021-9258(18)69392-5
Paul E. Waltonand, Terry D. Etherton, Stimulation of lipogenesis by insulin in swine adipose tissue: antagonism by porcine growth hormone. Journal of Animal Science. ,vol. 62, pp. 1584- 1595 ,(1986) , 10.2527/JAS1986.6261584X
L.J. Wardzala, B. Jeanrenaud, Potential mechanism of insulin action on glucose transport in the isolated rat diaphragm. Apparent translocation of intracellular transport units to the plasma membrane. Journal of Biological Chemistry. ,vol. 256, pp. 7090- 7093 ,(1980) , 10.1016/S0021-9258(19)68926-X
Y.T. Yang, R.L. Baldwin, Preparation and Metabolism of Isolated Cells from Bovine Adipose Tissue Journal of Dairy Science. ,vol. 56, pp. 350- 365 ,(1973) , 10.3168/JDS.S0022-0302(73)85178-1
Edward D. Renner, Peter G.W. Plagemann, Robert W. Bernlohr, Permeation of Glucose by Simple and Facilitated Diffusion by Novikoff Rat Hepatoma Cells in Suspension Culture and Its Relationship to Glucose Metabolism Journal of Biological Chemistry. ,vol. 247, pp. 5765- 5776 ,(1972) , 10.1016/S0021-9258(19)44825-4
J M May, D C Mikulecky, Glucose utilization in rat adipocytes. The interaction of transport and metabolism as affected by insulin. Journal of Biological Chemistry. ,vol. 258, pp. 4771- 4777 ,(1983) , 10.1016/S0021-9258(18)32491-8
Arne N. Wick, Douglas R. Drury, Henry I. Nakada, Jack B. Wolfe, Barbara Britton, Ruth Grabowski, LOCALIZATION OF THE PRIMARY METABOLIC BLOCK PRODUCED BY 2-DEOXYGLUCOSE Journal of Biological Chemistry. ,vol. 224, pp. 963- 969 ,(1957) , 10.1016/S0021-9258(18)64988-9
M Kuroda, R C Honnor, S W Cushman, C Londos, I A Simpson, Regulation of insulin-stimulated glucose transport in the isolated rat adipocyte. cAMP-independent effects of lipolytic and antilipolytic agents. Journal of Biological Chemistry. ,vol. 262, pp. 245- 253 ,(1987) , 10.1016/S0021-9258(19)75918-3