Insulin Binding and Glucose Transport

摘要: Publisher Summary This chapter discusses the insulin binding and glucose transport. The is explained with help of recent data on cellular localization, cooperativity, regulation receptors in normal transformed cells. action starts hormone to specific plasma membrane target Studies require a satisfactory reagent probe, one same biological properties as native insulin. monoiodinated has activity similar insulin, based stimulation oxidation by fat For transport, reviews various regulatory aspects, such cell growth, adaptation, hormonal influences neoplastic focuses mechanism transport cells where transported facilitated diffusion. process mediated carrier but does not energy; therefore, direction flux accordance its concentration gradient. most common experimental design for measuring rates substrate zero-trans influx procedure.