A Genetic Approach to the Study of Juvenile Hormone Control of Vitellogenesis in Drosophila melanogaster

摘要: Juvenile hormone (JH) is a key agent in the regulation of insect development, and thus it must effect proper gene management during ontogeny. How this occurs as yet mystery, but JH can alter chromosome function assayed by puffing polytene chromosomes Diptera (Lezzi Gilbert, 1969) models based on have been presented for its action (Williams Kafatos, 1971). Therefore seems appropriate to approach study from genetic standpoint. Mutant genes causing defects Drosophila might be expected develop lethal morphogenetic irregularities embryonic, larval, or pupal stages (Dearden, 1964; Bryant Sang, 1968; Ashburner, 1970; Madhavan, 1973; Postlethwait, 1974). Studying biochemistry these moribund animals reveal only frustrating artifacts. A more convenient system involve tissue which responds unnecessary individual’s survival. For example, many insects required some step oogenesis (see Doan, Engelmann, 1970). hormonal control due several factors. females lay up 60% their weight per day eggs (King et al., 1955; David 1968), indicates prodigious biosynthetic activity directed toward oogenesis. Furthermore, ultrastructure normal has very carefully described King (1970). Finally, great female sterile mutants are known Mohler, 1975). Our investigation exploits properties following three points regarding oogenesis: (1) What endocrinology melanogaster? (2) altered action? (3) does act appearance specific proteins developing oocytes?