Hydrogels in endovascular embolization. V. Antitumour agent methotrexate-containing p(HEMA).
作者： Daniel Horák , František Švec , Arnold Adamyan , Mariya Titova , Nikolai Skuba
DOI: 10.1016/0142-9612(92)90041-L
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摘要: Abstract The aminohexyl derivative of the copolymer 2-hydroxyethyl methacrylate and ethylene dimethacrylate (p(HEMA)-Hex) in form regular spherical particles was used as a polymeric carrier for chemically sorbed methotrexate (MTX). effect washed p(HEMA)-Hex-MTX on morphological structure donor blood, blood coagulation indicators responses living tissue surrounding material which had been vessel rabbit various periods time evaluated. MTX is capable diffusion several days from embolie material.
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