Residual neuromuscular blockade: incidence, assessment, and relevance in the postoperative period.

作者: G S Murphy

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摘要: The residual effects of neuromuscular blocking agents may persist into the early postoperative recovery period, even when blockade is carefully monitored and reversed in operating room. Recent data suggest that mild degrees paresis (train-of-four TOF ratios 0.7-0.9) be associated with significant impairment respiratory pharyngeal muscle function. Therefore, new gold standard reflecting acceptable a ratio > or =0.9. Several investigations have demonstrated many patients continue to arrive postanesthesia care unit <0.7-0.9. techniques used reduce risk paresis, which include avoidance long-acting relaxants, use monitoring room, routine reversal at count 2-3, administration agents. Careful management limit occurrence adverse events paralysis. Large-scale outcome studies are needed clearly define impact block on major morbidity mortality surgical patients.

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