Are SAR tables obsolete

作者: Celerino Abad-Zapatero

DOI: 10.1016/J.DRUDIS.2016.12.002

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参考文章(5)
Didier Roche, Denis Carniato, Caroline Leriche, Franck Lepifre, Serge Christmann-Franck, Ulrich Graedler, Christine Charon, Sophie Bozec, Liliane Doare, Fabien Schmidlin, Marc Lecomte, Eric Valeur, Discovery and structure–activity relationships of pentanedioic acid diamides as potent inhibitors of 11β-hydroxysteroid dehydrogenase type I Bioorganic & Medicinal Chemistry Letters. ,vol. 19, pp. 2674- 2678 ,(2009) , 10.1016/J.BMCL.2009.03.140
Cele Abad-Zapatero, Ognjen Perišić, John Wass, A. Patrícia Bento, John Overington, Bissan Al-Lazikani, Michael E. Johnson, Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation Drug Discovery Today. ,vol. 15, pp. 804- 811 ,(2010) , 10.1016/J.DRUDIS.2010.08.004
Serge Christmann-Franck, Daniel Cravo, Cele Abad-Zapatero, Time‐Trajectories in Efficiency Maps as Effective Guides for Drug Discovery Efforts Molecular Informatics. ,vol. 30, pp. 137- 144 ,(2011) , 10.1002/MINF.201000158
Franck Lepifre, Serge Christmann-Franck, Didier Roche, Caroline Leriche, Denis Carniato, Christine Charon, Sophie Bozec, Liliane Doare, Fabien Schmidlin, Marc Lecomte, Eric Valeur, Discovery and structure-guided drug design of inhibitors of 11β-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold Bioorganic & Medicinal Chemistry Letters. ,vol. 19, pp. 3682- 3685 ,(2009) , 10.1016/J.BMCL.2009.02.123