Acupuncture and vitamin B12 injection for Bell's palsy: no high-quality evidence exists.

摘要: OBJECTIVE: To assess the efficacy of acupuncture combined with vitamin B 12 acupoint injection versus alone to reduce incomplete recovery in patients Bell's palsy. DATA RETRIEVAL: A computer-based online retrieval Medline, Web Science, CNKI, CBM databases until April 2014 was performed for relevant trials, using key words palsy or idiopathic facial and methylcobalamin. STUDY SELECTION: All randomized controlled trials that compared were included meta-analysis. The initial treatment lasted at least 4 weeks. outcomes monitored. scoring index varied definition healing consistent. effect size calculated by relative risk ( RR ) 95% confidence interval CI fixed model Review Manager. MAIN OUTCOME MEASURES: Incomplete rates chosen as primary outcome. RESULTS: Five studies involving 344 final analysis. Results showed rate 44.50% group but 62.57% group. major acupoints Taiyang (EX-HN5), Jiache (ST6), Dicang (ST4) Sibai (ST2). better than = 0.71, : 0.58-0.87; P 0.001), this result held true when 8 lost follow up one study into analyses 0.70, 0.58-0.86; 0.0005). In subgroup analyses, therapeutic electroacupuncture non-electroacupuncture 0.024). There no significant difference analysis on drug types period. Most moderate low quality, bias existed. CONCLUSION: palsy, can our Because methodological limitations, conclusion is uncertain clinical application requires further exploration.