Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): A proof-of-concept, multicentre, open-label, phase 2 trial

作者: Andrea Sartore-Bianchi , Livio Trusolino , Cosimo Martino , Katia Bencardino , Sara Lonardi

DOI: 10.1016/S1470-2045(16)00150-9

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摘要: … cetuximab or panitumumab), an Eastern Cooperative Oncology Group performance status of 0 or 1, … We defined HER2 positivity in tumour samples by use of immunohistochemistry and …

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