The binocular input to cells in the feline dorsal lateral geniculate nucleus (dLGN).

摘要: 1. Cells in the A laminae of dorsal lateral geniculate nucleus receive their primary innervation from either contralateral (A) or ipsilateral (A1) eye. This paper provides evidence concerning responses they give to visual stimulation what is commonly regarded as ineffective non-dominant It also examines contribution corticofugal input these responses. 2. were identified and classified according dominant eye receptive field. was then occluded corresponding location field stimulated by a moving bar. Out fifty-seven cells examined forty-three (75%) gave response There no obvious difference between effects on X Y experiments. 3. In most cases (thirty-seven) involved an inhibition resting discharge level, but three mixed excitatory inhibitory pure response. All weak only revealed prolonged periods averaging (20-100 trials). 4. Ionophoretic application GABA antagonist N-methyl-bicuculline (NMB) blocked visually elicited (twenty-seven out thirty-two tested) further eight previously unresponsive eye, NMB three. 5. Increasing background levels cell excitability ionophoretic acetylcholine amino acid, quisqualate, did not eliminate reveal We suggest that driven suppression involves GABA-mediated which masks underlying input. 6. An could potentially derive influence projection. However, removal aspiration areas 17 18 reduce components 7. absence all tested (fourteen) exhibited studied during (eleven) The effect removing appeared involve loss 'damping' responses, such more easily revealed. significance findings discussed.