Inhibition of adjuvant-induced arthritis by nasal administration of novel synthetic peptides from heat shock protein 65

作者: Xiao-Lian Shi , Li-Ping Wang , Xuan Feng , Dan-Dan Fan , Wei-Jin Zang

DOI: 10.1186/1471-2474-15-253

关键词:

摘要: Background Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease mediated by T cells. The aim of the present study was to investigate therapeutic efficacy synthetic peptides (HP-R1, HP-R2 and HP-R3), derived from sequence 65-kD mycobacterial heat shock protein (HSP), in treatment RA using adjuvant-induced (AA) animal model.

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