Treatment of advanced and refractory breast cancer with doxorubicin, vincristine and continuous infusion of verapamil. A phase I-II clinical trial.

作者: M. Dicato , F. Ries

DOI: 10.1007/BF02988570

关键词:

摘要: Cancer cell resistance to several cytotoxic drugs, inclucling doxorubicin and vincristine can be reducedin vitro by verapamil; this drug works at least in part inhibitive competition for the multiple-drug effluxpump P-glycoprotein-170.

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