p16 gene methylation in colorectal cancers associated with Duke’s staging
作者： Jing Yi , Zhi-Wei Wang , Hui Cang , Yu-Ying Chen , Ren Zhao
关键词:
摘要: AIM: To explore the association of methylation CpG island in promotor P16 tumor suppressor gene with clinicopathological characteristics colorectal cancers. METHODS: Methylation-specific PCR (MSP) was used to detect 62 sporadic cancer specimens. RESULTS: detected 42% tumors. Dukes’ staging associated status. p16 occurred more frequently C and D patients (75.9%) than A B (12.1%). CONCLUSION: plays a role carcinogenes is subset cancer, it might be linked poor prognosis.
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