Association between local atherosclerosis and renal cell carcinomas.

作者: Martina Hager , Gregor Mikuz , Christian Kolbitsch , Patrizia Lucia Moser

DOI: 10.1080/01635580802067241

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摘要: Objective: Atherosclerosis induce changes in reactive oxygen species and oxidative stress by hypoxia leading to DNA damage therefore it could be expected that the cancer risk patients with atherosclerotic diseases is increased. Materials Methods: The present study aimed morphometrically compare (e.g., intima-to-media ratio [IMR]) renal cell (n = 514) tumor-negative specimens 70). Results: Renal specimens, contrast had more advanced lesions, which moreover immediately peritumorous (near-field) arteries were strongly developed than somewhat distant (far-field) arteries. IMR > 1 was significantly associated carcinoma odds of having higher for an 1. Conclusion: Local atherosclerosis pronounced tumor-positive with...

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