Health and economic impact of the seasonal influenza vaccination programme in England.
作者： Marc Baguelin , Mark Jit , Elizabeth Miller , William John Edmunds , None
DOI: 10.1016/J.VACCINE.2012.03.019
关键词:
摘要: Abstract Background The seasonal influenza vaccination programme in England targets individuals over 65 years old and clinical risk groups. Methods A model of transmission disease was fitted to weekly primary care consultations due a typical pre-pandemic season (2006/2007). Different scenarios were constructed about severity how well vaccines match circulating strains assess the impact cost-effectiveness current programme. Results well-matched vaccine may reduce incidence laboratory-confirmed illness from 8.2% (95% range 4.3–13%) 5.9% 2.9–9.7%), with 56–73% this indirect protection. is likely be cost-effective unless both low poor matching assumed. Conclusion appears substantially burden provides good value for money.
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