Evaluation of virulence factors of Candida albicans isolated from HIV-positive individuals using HAART
作者： Ralciane de Paula Menezes , Érika Bezerra de Melo Riceto , Aércio Sebastião Borges , Denise Von Dolingër de Brito Röder , Reginaldo dos Santos Pedroso
DOI: 10.1016/J.ARCHORALBIO.2016.02.004
关键词:
摘要: The colonization by Candida species is one of the most important factors related to development oral candidiasis in HIV-infected individuals. aim study was evaluate and discuss phospholipase, proteinase, DNAse haemolytic activities albicans isolated from cavity HIV individuals with high efficiency antiretroviral therapy. Seventy-five isolates C. obtained saliva samples patients 41 HIV-negative were studied. Haemolytic activity determined Sabouraud dextrose agar plates containing 3% glucose 7% sheep red cells. Culture medium DNA base-agar, egg yolk, bovine albumin used determine DNase, phospholipase proteinase activities, respectively. All group had activity, 98% showed 92% positive for 32% activity. Regarding individios negative, all presented hemolytic 90.2% 12.2% DNAse. more intense DNase production frequently observed HIV-positive percentage having also significantly different between groups not using any therapy, those transcriptase inhibitors inhibitor protease combination.
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