Tissue Transplantation in Diverse Marine Invertebrates

摘要: The search for the origins and early mechanisms of immunocompetence among invertebrates is now well underway. Tissue transplantation recognized as a sensitive perhaps universally applicable tool investigation immunoresponsiveness. Indeed, only orthotopic tissue may allow meaningful comparisons reactivity to potentially immunogenic cells phylogenetically diverse animals. This because responses xenogeneic or exotic macromolecules be limited by enzymes available species rather than immunologic potential such. Moreover, endotoxins inherent in many microbial antigen preparations have effects ranging from stimulating fatal, depending on recipient species. A purified protein such bovine serum albumin an excellent, satisfactory, poor immunogen whether rabbit, goldfish, mouse, respectively (Vredevoe, 1964, Trump, 1970). Thus choice test innate capacity decisive thus, results can misleading.