Synthesis of tetrasubstituted imidazoles via α-(N-acyl-N-alkylamino)-β-ketoamides on Wang resin
作者： Chengzhi Zhang , Edmund J Moran , Thomas F Woiwode , Kevin M Short , Adnan M.M Mjalli
DOI: 10.1016/0040-4039(95)02310-0
关键词:
摘要: The first example of a four component condensation arylglyoxals, 1° amines, carboxylic acids and isocyanides on Wang resin is described. These products can be cyclized in the presence NH4OAcAcOH to yield tetrasubstituted imidazoles.
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