Dietary fibre-rich resistant starches promote ammonia detoxification in the human colon as measured by lactose-[¹⁵N₂]ureide.

摘要: Three resistant starches (RSs), namely fibre of potatoes (FP), wrinkle pea starch (WPS), and high amylose maize (HAMS) with different dietary contents, were supplemented in adults to evaluate their effects on urinary nitrogen ammonia excretion as well faecal by means lactose-[(15)N2]ureide ((15)N-LU) degradation. Twenty subjects received a regular diet either without or the supplementation FP, WPS, HAMS randomized order. After administration (15)N-LU, urine faeces collected over 48 72 h, respectively, whereas blood was after 6 h. The (15)N-abundances measured isotope ratio mass spectrometry. In comparison dry run, RS significantly lowered renal (15)N-excretion (dry run: 43.2%, FP: 34.6%, WPS: 37.9%, HAMS: 36.4%) corresponding (15)NH3-excretion 0.08%, 0.06%, 0.05%), clearly indicating reduced colonic generation at intake.