Differences in skin‐prick and patch‐test reactivity are related to the heterogeneity of atopic eczema in infants

作者: O. M. Kekki , K. Turjanmaa , E. Isolauri

DOI: 10.1111/J.1398-9995.1997.TB01234.X

关键词:

摘要: Current data indicate an obvious relation between food allergy and atopic eczema in infants. However, diagnostic methods for need to be supplemented. The objective was study the relevance of patch testing detection correlation with oral challenge skin prick tests Infants (n = 113) aged 2-24 months were studied. Each patient subjected double-blind, placebo-controlled, or open cow's milk challenge, tests. Polysensitization, as judged from test results, common patients (79/113). Cow's positive 54/113 infants; reactions immediate 36/54 delayed 18/54. Immediate-type associated positivity positivity. Altogether 26% milk-allergic infants detected by only. Patch improved accuracy diagnosis eczema, but it needs standardized. Polysensitization appears more than generally believed among eczema.

参考文章(16)
RobertL. Rietschel, Reproducibility of patch-test results The Lancet. ,vol. 347, pp. 1202- ,(1996) , 10.1016/S0140-6736(96)90731-X
Markus Grewe, Stefan Walther, Karin Gyufko, Wolfgang Czech, Erwin Schöpf, Jean Krutmann, Analysis of the Cytokine Pattern Expressed In Situ in Inhalant Allergen Patch Test Reactions of Atopic Dermatitis Patients Journal of Investigative Dermatology. ,vol. 105, pp. 407- 410 ,(1995) , 10.1111/1523-1747.EP12321078
Hugh A. Sampson, Sheila M. Scanlon, Natural history of food hypersensitivity in children with atopic dermatitis The Journal of Pediatrics. ,vol. 115, pp. 23- 27 ,(1989) , 10.1016/S0022-3476(89)80323-3
J.M. Bishop, D.J. Hill, C.S. Hosking, Natural history of cow milk allergy: Clinical outcome The Journal of Pediatrics. ,vol. 116, pp. 862- 867 ,(1990) , 10.1016/S0022-3476(05)80641-9
A. Wesley Burks, Susan B. Mallory, Larry W. Williams, M. Annette Shirrell, Atopic dermatitis: clinical relevance of food hypersensitivity reactions. The Journal of Pediatrics. ,vol. 113, pp. 447- 451 ,(1988) , 10.1016/S0022-3476(88)80626-7
Frans L van der Heijden, Eddy A Wierenga, Jan D Bos, Martien L Kapsenberg, High frequency of IL-4-producing CD4+ allergen-specific T lymphocytes in atopic dermatitis lesional skin. Journal of Investigative Dermatology. ,vol. 97, pp. 389- 394 ,(1991) , 10.1111/1523-1747.EP12480966
Erika Isolauri, Kristiina Turjanmaa, Combined skin prick and patch testing enhances identification of food allergy in infants with atopic dermatitis The Journal of Allergy and Clinical Immunology. ,vol. 97, pp. 9- 15 ,(1996) , 10.1016/S0091-6749(96)70277-4