Additive manufacturing of nanocellulose based scaffolds for tissue engineering: Beyond a reinforcement filler.

摘要: Abstract Cellulose nanomaterials (CNMs) have attracted great attention in the last decades due to abundance of biopolymer, biorenewable character and outstanding mechanical properties they account for. These, together with their biocompatibility makes them ideal candidates for tissue engineering (TE) applications. Additive manufacturing is an biofabrication approach TE, providing rapid reliable technologies produce scaffolds aimed guidance host or implanted cells form functional tissues. However, control parameters at nanoscale that regulate cellular functions such as proliferation differentiation remain challenging. This review article presents latest advances use CNMs platforms guide additive manufactured scaffolds. Special given functionalization routes, methods exploit topographical cues improve local resulting cell-CNM interactions.