Analysis of symptomatic and asymptomatic primary root canal infections in adult Norwegian patients.

摘要: Abstract Introduction This molecular study analyzed the microbiota of primary root canal infections from adult Norwegian patients. Methods Samples were taken necrotic canals teeth with symptomatic (n = 13) or asymptomatic 21) apical periodontitis and chronic abscesses 9). DNA was extracted samples, bacterial identifications performed by a closed-ended reverse-capture checkerboard approach targeting 50 candidate endodontic pathogens. Results Bacterial detected in all cases. In periodontitis, most frequent taxa Dialister invisus (71%), Fusobacterium nucleatum (62%), Porphyromonas endodontalis (62%). abscesses, prevalent P. (100%), D. (89%), Parvimonas micra (78%), Solobacterium moorei (78%). , endodontalis, S. moorei, Propionibacterium acnes, Streptococcus species (all 69%). None targeted significantly associated either sinus tract pain ( P > .05), except for Selenomonas sputigena which more frequently found painful cases .04). No higher levels any conditions .05). Cluster analyses revealed groupings that differed between without pain. Conclusions Although basically same highly different examined none positively symptoms, results formed partnerships associations samples Therefore, it is possible virulent multispecies communities can form as result overall combinations give rise to acute inflammation.