Consistency of Sperm Morphology Classification Methods

摘要: : The World Health Organization (WHO) recently suggested new morphometric dimensions for normal sperm heads and head classification rules. These specifications differ from previous WHO methods the Kruger method strict morphology assessment. We analyzed rules to determine their appropriateness as predictive linear models. reviewed theoretical requirements allometric modeling, a more traditional approach specifying size relationships between phenotypic characters, developed valid models based on statistical properties of over 3,700 measurements individual dimensions. implemented WHO, Kruger, Allometric same set digitized study empirical consequences different metric methods. Results show that are internally consistent, but specify nonconstant variance. Hence, they inappropriate were consistent specified constant appropriate Significant differences found in percentage On average, produced lowest value significantly higher values than methods, no average difference was or Nevertheless, did change specimens. results indicate small can dramatically sperm. Until rig-orous definitions features be developed, used describe population characteristics fertile sperm, prognostic is limited.