Adjuvant Treatment of Colon and Rectal Cancer: Impact of Chemotherapy, Radiotherapy, and Immunotherapy on Routine Postsurgical Patient Management

作者: K. H. Link , L. Staib , E.-D. Kreuser , H. G. Beger

DOI: 10.1007/978-3-642-80035-1_19

关键词:

摘要: Colon cancer patients with UICC stage III or T4 N0 M0 II should receive postoperative adjuvant therapy, since relapse rates are high and surgical outcome has been improved by treatment. The standard treatment is 5-fluourouracil plus levamisole; an alternative option the combination of folinic acid. Stage (T3 M0) colon not outside studies.Rectal radiochemotherapy 45–54.4 Gy as Patients eligible for radiotherapy may chemotherapy only. Studies need to be conducted improve therapy in colorectal cancer. All qualified treated within these studies requiring sufficient patient numbers, well comparable procedures, proper selection stratification criteria, drug dose intensities.

参考文章(151)
Anders Österborg, Peter WersÄll, Jan Fagerberg, Giuseppe Masucci, Jan-Erik FrÖdin, Peter Ragnhammar, HÅkan Mellstedt, Anna-Lena Hjelm, Chemotherapy and immunotherapy of colorectal cancer Medical Oncology and Tumor PharmacoTherapy. ,vol. 8, pp. 207- 220 ,(1991) , 10.1007/BF02987181
Survival after postoperative combination treatment of rectal cancer. The New England Journal of Medicine. ,vol. 315, pp. 1294- 1295 ,(1986) , 10.1056/NEJM198611133152014
WILLIAM R. WELCH, STANLEY J. ROBBOY, DUANE E. TOWNSEND, ANN B. BARNES, ROBERT E. SCULLY, ARTHUR L. HERBST, Comparison of Histologic and Colposcopic Findings in Des-exposed Females Annals of Surgery. ,vol. 189, pp. 332- 333 ,(1979) , 10.1097/00000658-197904000-00027
Cancer statistics, 1989. CA: A Cancer Journal for Clinicians. ,vol. 39, pp. 3- 20 ,(1989) , 10.3322/CANJCLIN.39.1.3
Steven A. Rosenberg, Surgical treatment of metastatic cancer Lippincott. ,(1987)
Harry Bleiberg, The future of adjuvant treatment in gastrointestinal cancer. Ejso. ,vol. 16, pp. 189- 194 ,(1990)
William Harel, Malcolm S. Mitchell, Ludger Staib, Protection against Experimental Cerebral Metastases of Murine Melanoma B16 by Active Immunization Cancer Research. ,vol. 53, pp. 1113- 1121 ,(1993)
A. Barth, Dave SB Hoon, Leland J Foshag, J Anne Nizze, E. Famatiga, E. Okun, Donald L Morton, Polyvalent Melanoma Cell Vaccine Induces Delayed-Type Hypersensitivity and in Vitro Cellular Immune Response Cancer Research. ,vol. 54, pp. 3342- 3345 ,(1994)