The aluminium-amyloid cascade hypothesis and Alzheimer's disease.
作者： Christopher Exley
关键词:
摘要: … In our recent study Al was a prerequisite to amyloid fibril formation. Whether Al could act as a nidus for the precipitation of Ap42 as P-pleated sheets in vivo must now be considered a …
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Christopher Exley, Olga Korchazhkina, Chapter 22 – The Association of Aluminium and β Amyloid in Alzheimer’s Disease Aluminium and Alzheimer's Disease#R##N#The Science that Describes the Link. pp. 421- 433 ,(2001) , 10.1016/B978-044450811-9/50047-1
Emily House, Joanna Collingwood, Ayesha Khan, Olga Korchazkina, Guy Berthon, Christopher Exley, Aluminium, iron, zinc and copper influence the in vitro formation of amyloid fibrils of Aβ42 in a manner which may have consequences for metal chelation therapy in Alzheimer's disease Journal of Alzheimer's Disease. ,vol. 6, pp. 291- 301 ,(2004) , 10.3233/JAD-2004-6310
Julie A. Carson, Anthony J. Turner, β‐Amyloid catabolism: roles for neprilysin (NEP) and other metallopeptidases? Journal of Neurochemistry. ,vol. 81, pp. 1- 8 ,(2002) , 10.1046/J.1471-4159.2002.00855.X
Olga V. Korchazhkina, Alison E. Ashcroft, Tamas Kiss, Christopher Exley, The degradation of Aβ25–35 by the serine protease plasmin is inhibited by aluminium Journal of Alzheimer's Disease. ,vol. 4, pp. 357- 367 ,(2002) , 10.3233/JAD-2002-4503
Christopher Exley, Nicholas C. Price, Sharon M. Kelly, J.Derek Birchall, An interaction of β-amyloid with aluminium in vitro FEBS Letters. ,vol. 324, pp. 293- 295 ,(1993) , 10.1016/0014-5793(93)80137-J
Serge Duckett, P. Galle, ELECTRON MICROSCOPE-MICROPROBE STUDIES OF ALUMINUM IN THE BRAINS OF CASES OF ALZHEIMERʼS DISEASE AND AGEING PATIENTS Journal of Neuropathology and Experimental Neurology. ,vol. 39, pp. 350- ,(1980) , 10.1097/00005072-198005000-00048
Julie A Varner, Karl F Jensen, William Horvath, Robert L Isaacson, Chronic administration of aluminum-fluoride or sodium-fluoride to rats in drinking water: alterations in neuronal and cerebrovascular integrity Brain Research. ,vol. 784, pp. 284- 298 ,(1998) , 10.1016/S0006-8993(97)01336-X
Diane Beauchemin, Robert Kisilevsky, A Method Based on ICP-MS for the Analysis of Alzheimer's Amyloid Plaques Analytical Chemistry. ,vol. 70, pp. 1026- 1029 ,(1998) , 10.1021/AC970783F
M. Clauberg, J. G. Joshi, Regulation of serine protease activity by aluminum: implications for Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 1009- 1012 ,(1993) , 10.1073/PNAS.90.3.1009
Zhang-Jin Zhang, Yi-Hua Qian, Hai-Tao Hu, Jie Yang, Guang-De Yang, The herbal medicine Dipsacus asper Wall extract reduces the cognitive deficits and overexpression of β-amyloid protein induced by aluminum exposure Life Sciences. ,vol. 73, pp. 2443- 2454 ,(2003) , 10.1016/S0024-3205(03)00649-0