Antibacterial iridoid glucosides from Eremostachys laciniata
作者： Masoud Modaressi , Abbas Delazar , Hossein Nazemiyeh , Fatemeh Fathi-Azad , Eileen Smith
DOI: 10.1002/PTR.2568
关键词:
摘要: Eremostachys laciniata (L) Bunge (family: Lamiaceae alt. Labiatae; subfamily: Lamioideae) is one of the 15 endemic Iranian herbs genus Eremostachys. A decoction roots and flowers E. has traditionally been taken orally for treatment allergies, headache liver diseases. Three antibacterial iridoid glucosides, phloyoside I (1), phlomiol (2) pulchelloside (3) have isolated from rhizomes this plant. The structures these compounds were elucidated unequivocally by a series 1D 2D NMR analyses. activity brine shrimp toxicity assessed using resazurin microtitre assay lethality assay, respectively. All three glycosides 1-3 exhibited low to moderate levels (MIC = 0.05-0.50 mg/mL) activity. Of compounds, compound 3 was most active, displayed against 9 12 different strains tested. noteworthy Bacillus cereus, penicillin-resistant Escherichia coli, Proteus mirabilis Staphylococcus aureus with an MIC value 0.05 mg/mL.
cabdirect.org
sci-hub.se 参考文章(31)
Lotte Boe Frederiksen, Søren Damtoft, Søren Rosendal Jensen, Biosynthesis of iridoids lacking C-10 and the chemotaxonomic implications of their distribution Phytochemistry. ,vol. 52, pp. 1409- 1420 ,(1999) , 10.1016/S0031-9422(99)00244-7
Ryoji Kasai, Masako Katagiri, Kazuhiro Ohtani, Kazuo Yamasaki, Yang Chong-Ren, Osamu Tanaka, Iridoid glycosides from Phlomis younghusbandii roots Phytochemistry. ,vol. 36, pp. 967- 970 ,(1994) , 10.1016/S0031-9422(00)90473-4
Abbas Delazar, Masoud Modarresi, Mohammad Shoeb, Lutfun Nahar, Raymond G. Reid, Yashodharan Kumarasamy, Runner R. T. Majinda, Satyajit D. Sarker, Eremostachiin: a new furanolabdane diterpene glycoside from Eremostachys glabra. Natural Product Research. ,vol. 20, pp. 167- 172 ,(2006) , 10.1080/13518470500047082
Kalina I Alipieva, Rilka M Taskova, Ljubka N Evstatieva, Nedjalka V Handjieva, Simeon S Popov, Benzoxazinoids and iridoid glucosides from four Lamium species Phytochemistry. ,vol. 64, pp. 1413- 1417 ,(2003) , 10.1016/J.PHYTOCHEM.2003.08.001
A. Delazar, M. Naseri, L. Nahar, S. B. Moghadam, S. Esnaashari, H. Nazemiyeh, S. D. Sarker, GC-MS analysis and antioxidant activities of essential oils of two cultivated Artemisia species Chemistry of Natural Compounds. ,vol. 43, pp. 112- 114 ,(2007) , 10.1007/S10600-007-0047-8
A. Delazar, S. Celik, R. S. Goektuerk, O. Unal, L. Nahar, S. D. Sarker, Two Acylated Flavonoid Glycosides from Stachys bombycina, and Their Free Radical Scavenging Activity. ChemInform. ,vol. 37, ,(2006) , 10.1002/CHIN.200610208
Cheng-Zhong Zhang, Chong Li, Shi-Ian Feng, Jian-Gong Shi, IRIDOID GLUCOSIDES FROM PHLOMIS ROTATA Phytochemistry. ,vol. 30, pp. 4156- 4158 ,(1991) , 10.1016/0031-9422(91)83486-5
Abbas Delazar, Maryam Naseri, Hossein Nazemiyeh, Amir-Hossein Talebpour, Yousef Imani, Lutfun Nahar, Satyajit D. Sarker, Flavonol 3-methyl ether glucosides and a tryptophylglycine dipeptide from Artemisia fragrans (Asteraceae) Biochemical Systematics and Ecology. ,vol. 35, pp. 52- 56 ,(2007) , 10.1016/J.BSE.2006.09.006
Abbas Delazar, Maureen Byres, Simon Gibbons, Yashodharan Kumarasamy, Masoud Modarresi, Lutfun Nahar, Mohammad Shoeb, Satyajit D. Sarker, Iridoid Glycosides from Eremostachys glabra Journal of Natural Products. ,vol. 67, pp. 1584- 1587 ,(2004) , 10.1021/NP040044B
Satyajit D. Sarker, Lutfun Nahar, Yashodharan Kumarasamy, Microtitre plate-based antibacterial assay incorporating resazurin as an indicator of cell growth, and its application in the in vitro antibacterial screening of phytochemicals. Methods. ,vol. 42, pp. 321- 324 ,(2007) , 10.1016/J.YMETH.2007.01.006