Spindle frequency activity in the sleep EEG: individual differences and topographic distribution

作者: Esther Werth , Peter Achermann , Derk-Jan Dijk , Alexander A. Borbély

DOI: 10.1016/S0013-4694(97)00070-9

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摘要: The brain topography of EEG power spectra in the frequency range sleep spindles was investigated 34 recordings from 20 healthy young men. Referential (F3-A2, C3-A2, P3-A2 and O1-A2) bipolar derivations (F3-C3, C3-P3 P3-O1) along anteroposterior axis were used. Sleep gave rise to a distinct peak spectrum. distribution frequencies pooled over subjects showed bimodal pattern with modes at 11.5 13.0 Hz, trough 12.25 Hz. large inter-subject variation (range: 1.25 Hz) contrasted small intra-subject between derivations, non-REM episodes different nights. In some individuals and/or only single spindle present. topographic distributions referential differences. declining trend consecutive low activity rising high range. functional heterogeneity conjunction stability their are important characteristics for analysis regulation on basis EEG.

参考文章(32)
J.-M. Gaillard, R. Blois, Spindle Density in Sleep of Normal Subjects Sleep. ,vol. 4, pp. 385- 391 ,(1981) , 10.1093/SLEEP/4.4.385
D. Aeschbach, C. Cajochen, H. Landolt, A. A. Borbely, Homeostatic sleep regulation in habitual short sleepers and long sleepers American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 270, ,(1996) , 10.1152/AJPREGU.1996.270.1.R41
J.C. Hirsch, A. Fourment, M.E. Marc, Sleep-related variations of membrane potential in the lateral geniculate body relay neurons of the cat Brain Research. ,vol. 259, pp. 308- 312 ,(1983) , 10.1016/0006-8993(83)91264-7
Derk-Jan Dijk, Boyd Hayes, Charles A. Czeisler, Dynamics of electroencephalographic sleep spindles and slow wave activity in men: effect of sleep deprivation. Brain Research. ,vol. 626, pp. 190- 199 ,(1993) , 10.1016/0006-8993(93)90579-C
Hans Peter Landolt, Derk-Jan Dijk, Stephanie E Gaus, Alexander A Borbély, Caffeine reduces low-frequency delta activity in the human sleep EEG Neuropsychopharmacology. ,vol. 12, pp. 229- 238 ,(1995) , 10.1016/0893-133X(94)00079-F
Derk-Jan Dijk, Corinne Roth, Hans-Peter Landolt, Esther Werth, Michael Aeppli, Peter Achermann, Alexander A. Borbély, Melatonin effect on daytime sleep in men: suppression of EEG low frequency activity and enhancement of spindle frequency activity. Neuroscience Letters. ,vol. 201, pp. 13- 16 ,(1995) , 10.1016/0304-3940(95)12118-N
Alexander A. Borbély, Derk-Jan Dijk, Hans-Peter Landolt, Esther Werth, Caffeine intake (200 mg) in the morning affects human sleep and EEG power spectra at night. Brain Research. ,vol. 675, pp. 67- 74 ,(1995) , 10.1016/0006-8993(95)00040-W
Alexander A. Borbély, Peter Mattmann, Maija Loepfe, Isabel Fellmann, Margaret Gerne, Inge Strauch, Dietrich Lehmann, A single dose of benzodiazepine hypnotics alters the sleep EEG in the subsequent drug-free night. European Journal of Pharmacology. ,vol. 89, pp. 157- 161 ,(1983) , 10.1016/0014-2999(83)90622-2