Sex-dependent association of ACE (I/D) polymorphism with Meniere's disease
作者： Mohammad Mohseni , Nasrin Yazdani , Saeedeh Asgarbeik , Ahmad Daneshi , Mohammad Farhadi
DOI: 10.1016/J.MGENE.2020.100659
关键词:
摘要: Abstract Background Meniere's disease is an inner ear disorder presenting with recurrent episodic vertigo, fluctuating sensorineural hearing loss, tinnitus, and aural fullness as its main symptoms. Previous studies have demonstrated the role of blood pressure in disease. The purpose this study was to determine ACE, rs4646994 I/D polymorphism Methods materials In case-control study, 67 individuals 100 healthy a control group were enrolled. Patients DNA samples extracted from by phenol-chloroform method. frequency genotypes determined polymerase chain reaction (PCR) technique. Results allele frequencies not significantly different between studied populations (p > .05). There significant differences for distribution genotype females males (p Conclusions This demonstrates gender association ACE Iranian population.
sci-hub.st 参考文章(39)
B.A. Bhavani, T. Padma, B.K.S. Sastry, N. Krishna Reddy, Gender Specific Association of Insertion/Deletion Polymorphism of the Human Angiotensin Converting Enzyme Gene with Essential Hypertension International Journal of Human Genetics. ,vol. 4, pp. 207- 213 ,(2004) , 10.1080/09723757.2004.11885894
Shamila G. Rawal, Kunal H. Thakkar, Kasra Ziai, Peter A. Santi, Hamid R. Djalilian, HLA-B27-associated bilateral Ménière disease Ear, nose, & throat journal. ,vol. 89, pp. 122- 127 ,(2010) , 10.1177/014556131008900309
Mari Havia, Erna Kentala, Ilmari PyykkÖ, Prevalence of Menière's disease in general population of Southern Finland. Otolaryngology-Head and Neck Surgery. ,vol. 133, pp. 762- 768 ,(2005) , 10.1016/J.OTOHNS.2005.06.015
Yukio Watanabe, Michiro Fujisaka, Masahito Tsubota, Kenji Kobayashi, Satsuki Yasumura, Kanemasa Mizukoshi, Hideo Shojaku, Epidemiologic characteristics of definite Ménière's disease in Japan. A long-term survey of Toyama and Niigata prefectures. Operations Research Letters. ,vol. 67, pp. 305- 309 ,(2005) , 10.1159/000089413
A. Stanković, M. Zivković, D. Alavantić, Angiotensin I-converting enzyme gene polymorphism in a Serbian population: a gender-specific association with hypertension. Scandinavian Journal of Clinical & Laboratory Investigation. ,vol. 62, pp. 469- 475 ,(2002) , 10.1080/00365510260390028
Cinzia Fatini, Serena Guiducci, Rosanna Abbate, Marco Matucci-Cerinic, Vascular injury in systemic sclerosis: Angiotensin-converting enzyme insertion/deletion polymorphism Current Rheumatology Reports. ,vol. 6, pp. 149- 155 ,(2004) , 10.1007/S11926-004-0060-X
D. Al-Mana, B. Ceranic, O. Djahanbakhch, L.M. Luxon, Hormones and the auditory system: a review of physiology and pathophysiology. Neuroscience. ,vol. 153, pp. 881- 900 ,(2008) , 10.1016/J.NEUROSCIENCE.2008.02.077
Ricardo Rodrigues Figueiredo, Andréia Aparecida de Azevedo, Norma de Oliveira Penido, Tinnitus and arterial hypertension: a systematic review European Archives of Oto-rhino-laryngology. ,vol. 272, pp. 3089- 3094 ,(2015) , 10.1007/S00405-014-3277-Y
A. Greco, A. Gallo, M. Fusconi, C. Marinelli, G.F. Macri, M. de Vincentiis, Meniere's disease might be an autoimmune condition? Autoimmunity Reviews. ,vol. 11, pp. 731- 738 ,(2012) , 10.1016/J.AUTREV.2012.01.004
Kai-Jen Tien, Jeng-Yueh Hsiao, Shih-Chieh Hsu, Hui-Ting Liang, Shiu-Ru Lin, Hung-Chun Chen, Ming-Chia Hsieh, Gender-dependent effect of ACE I/D and AGT M235T polymorphisms on the progression of urinary albumin excretion in Taiwanese with type 2 diabetes. American Journal of Nephrology. ,vol. 29, pp. 299- 308 ,(2009) , 10.1159/000163592