Nonsteroidal anti-inflammatory drugs.

作者: Carin E. Dugowson , Priya Gnanashanmugam

DOI: 10.1016/J.PMR.2005.12.012

关键词:

摘要: Nonsteroidal anti-inflammatory drugs, including COX-2 selective are often used for acute and chronic musculoskeletal pain,including osteoarthritis, trauma, overuse syndromes, compression fractures. Although these medications well tolerated in the young otherwise healthy patient, use of can lead to multiple medical problems, most commonly related gastrointestinal tract. Recently, concerns about cardiovascular adverse effects have been raised, particularly drugs. Dosing duration therapy should be adjusted comorbidities. CBC renal hepatic function checked at intervals 3 6 months, depending on patient.

参考文章(26)
K. Osterman, T. Videman, Double-blind parallel study of piroxicam versus indomethacin in the treatment of low back pain Annals of clinical research. ,vol. 16, pp. 156- 160 ,(1984)
Hickey Rf, Chronic low back pain: a comparison of diflunisal with paracetamol. The New Zealand Medical Journal. ,vol. 95, pp. 312- 314 ,(1982)
Alaa Rostom, Catherine Dube, George A Wells, Peter Tugwell, Vivian Welch, Emilie Jolicoeur, Jessie McGowan, Angel Lanas, Prevention of NSAID-induced gastroduodenal ulcers. Cochrane Database of Systematic Reviews. ,(2002) , 10.1002/14651858.CD002296
Sarah E Garner, Dogan Fidan, Ruth R Frankish, Maria Judd, Beverley Shea, Tanveer Towheed, Peter Tugwell, George A Wells, Celecoxib for rheumatoid arthritis Cochrane Database of Systematic Reviews. ,(2017) , 10.1002/14651858.CD003831
Pepijn DDM Roelofs, Rick A Deyo, Bart W Koes, Rob JPM Scholten, Maurits W van Tulder, None, Non‐steroidal anti‐inflammatory drugs for low‐back pain Cochrane Database of Systematic Reviews. ,vol. 2000, ,(2008) , 10.1002/14651858.CD000396.PUB3
Thomas J Schnitzer, Aimee Ferraro, Elke Hunsche, Sheldon X Kong, A comprehensive review of clinical trials on the efficacy and safety of drugs for the treatment of low back pain Journal of Pain and Symptom Management. ,vol. 28, pp. 72- 95 ,(2004) , 10.1016/J.JPAINSYMMAN.2003.10.015
Francis K.L. Chan, Lawrence C.T. Hung, Bing Y. Suen, Vincent W.S. Wong, Aric J. Hui, Justin C.Y. Wu, Wai K. Leung, Yuk T. Lee, Ka F. To, S.C. Sydney Chung, Joseph J.Y. Sung, Celecoxib versus diclofenac plus omeprazole in high-risk arthritis patients: results of a randomized double-blind trial. Gastroenterology. ,vol. 127, pp. 1038- 1043 ,(2004) , 10.1053/J.GASTRO.2004.07.010
J.R Vane, R.M Botting, The mechanism of action of aspirin Thrombosis Research. ,vol. 110, pp. 255- 258 ,(2003) , 10.1016/S0049-3848(03)00379-7
M. R Weir, Renal effects of nonselective NSAIDs and coxibs. Cleveland Clinic Journal of Medicine. ,vol. 69, ,(2002) , 10.3949/CCJM.69.SUPPL_1.SI53