作者: Carin E. Dugowson , Priya Gnanashanmugam
DOI: 10.1016/J.PMR.2005.12.012
关键词:
摘要: Nonsteroidal anti-inflammatory drugs, including COX-2 selective are often used for acute and chronic musculoskeletal pain,including osteoarthritis, trauma, overuse syndromes, compression fractures. Although these medications well tolerated in the young otherwise healthy patient, use of can lead to multiple medical problems, most commonly related gastrointestinal tract. Recently, concerns about cardiovascular adverse effects have been raised, particularly drugs. Dosing duration therapy should be adjusted comorbidities. CBC renal hepatic function checked at intervals 3 6 months, depending on patient.