The prediction of the porcine pre-microRNAs in genome-wide based on support vector machine (SVM) and homology searching

作者: Zhen Wang , Kan He , Qishan Wang , Yumei Yang , Yuchun Pan

DOI: 10.1186/1471-2164-13-729

关键词:

摘要: Background MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression by targeting mRNAs for translation repression or mRNA degradation. Although many miRNAs have been discovered and studied in human mouse, few studies focused on porcine miRNAs, especially genome wide.

参考文章(56)
Susan M. Rueter, T. Renee Dawson, Ronald B. Emeson, Regulation of alternative splicing by RNA editing Nature. ,vol. 399, pp. 75- 80 ,(1999) , 10.1038/19992
Bo ZHOU, Hong-Lin LIU, Computational identification of new porcine microRNAs and their targets Animal Science Journal. ,vol. 81, pp. 290- 296 ,(2010) , 10.1111/J.1740-0929.2010.00742.X
Davide Anguita, Andrea Boni, Sandro Ridella, Evaluating the Generalization Ability of Support Vector Machines through the Bootstrap Neural Processing Letters. ,vol. 11, pp. 51- 58 ,(2000) , 10.1023/A:1009636300083
Eva Freyhult, Paul P Gardner, Vincent Moulton, A comparison of RNA folding measures BMC Bioinformatics. ,vol. 6, pp. 241- 241 ,(2005) , 10.1186/1471-2105-6-241
Chenghai Xue, Fei Li, Tao He, Guo-Ping Liu, Yanda Li, Xuegong Zhang, Classification of real and pseudo microRNA precursors using local structure-sequence features and support vector machine BMC Bioinformatics. ,vol. 6, pp. 310- 310 ,(2005) , 10.1186/1471-2105-6-310
Ivo L. Hofacker, RNA Secondary Structure Analysis Using the Vienna RNA Package Current protocols in human genetics. ,vol. 26, ,(2003) , 10.1002/0471250953.BI1202S26
J.P. Hagan, C.M. Croce, MicroRNAs in carcinogenesis. Cytogenetic and Genome Research. ,vol. 118, pp. 252- 259 ,(2007) , 10.1159/000108308
Mariana Lagos-Quintana, Reinhard Rauhut, Abdullah Yalcin, Jutta Meyer, Winfried Lendeckel, Thomas Tuschl, Identification of tissue-specific microRNAs from mouse Current Biology. ,vol. 12, pp. 735- 739 ,(2002) , 10.1016/S0960-9822(02)00809-6
Carley Glass, Dinender K. Singla, ES cells overexpressing microRNA-1 attenuate apoptosis in the injured myocardium Molecular and Cellular Biochemistry. ,vol. 357, pp. 135- 141 ,(2011) , 10.1007/S11010-011-0883-5