Vitamin E and wound healing: an evidence-based review.
作者： Rachel Hobson
DOI: 10.1111/IWJ.12295
关键词:
摘要: Vitamin E has been demonstrated to modulate cellular signalling, gene expression and affect wounds infected with methicillin-resistant Staphylococcus aureus (MRSA), thus influencing wound healing. This evidence-based review aimed identify evaluate current research assessing the properties of vitamin in relation healing, through its role as an antioxidant influence on connective tissue growth factor (CTGF), MRSA transcription. Literature dated from 1996 2012, published English, involving either animals or adult humans acute chronic were included. The databases that contained relevant articles narrowed down four, a total 33 identified studies literature revealed there is significant dearth robust establishing effects further clearly warranted.
sci-hub.se 参考文章(50)
M. De la Fuente, M. Carazo, R. Correa, M. Del Río, Changes in macrophage and lymphocyte functions in guinea-pigs after different amounts of vitamin E ingestion British Journal of Nutrition. ,vol. 84, pp. 25- 29 ,(2000) , 10.1017/S0007114500001197
Alexandra Fischer, Josef Pallauf, Gerald Rimbach, Selenium- and vitamin E-dependent gene expression in rats: analysis of differentially expressed mRNAs. Methods in Enzymology. ,vol. 347, pp. 267- 276 ,(2002) , 10.1016/S0076-6879(02)47026-7
Anamika M. Rasik, Arti Shukla, Antioxidant status in delayed healing type of wounds. International Journal of Experimental Pathology. ,vol. 81, pp. 257- 263 ,(2001) , 10.1046/J.1365-2613.2000.00158.X
Sung Nim Han, Oskar Adolfsson, Cheol-Koo Lee, Tomas A. Prolla, Jose Ordovas, Simin Nikbin Meydani, Age and vitamin E-induced changes in gene expression profiles of T cells. Journal of Immunology. ,vol. 177, pp. 6052- 6061 ,(2006) , 10.4049/JIMMUNOL.177.9.6052
D Boscoboinik, A Szewczyk, C Hensey, A Azzi, Inhibition of cell proliferation by alpha-tocopherol. Role of protein kinase C. Journal of Biological Chemistry. ,vol. 266, pp. 6188- 6194 ,(1991) , 10.1016/S0021-9258(18)38102-X
S. Thomas, Cost of managing chronic wounds in the UK, with particular emphasis on maggot debridement therapy Journal of Wound Care. ,vol. 15, pp. 465- 469 ,(2006) , 10.12968/JOWC.2006.15.10.26973
S N Meydani, M Meydani, J B Blumberg, L S Leka, M Pedrosa, R Diamond, E J Schaefer, Assessment of the safety of supplementation with different amounts of vitamin E in healthy older adults. The American Journal of Clinical Nutrition. ,vol. 68, pp. 311- 318 ,(1998) , 10.1093/AJCN/68.2.311
Esther G Pallast, Evert G Schouten, Frouwkje G de Waart, Hannie C Fonk, Gert Doekes, B Mary von Blomberg, Frans J Kok, Effect of 50- and 100-mg vitamin E supplements on cellular immune function in noninstitutionalized elderly persons The American Journal of Clinical Nutrition. ,vol. 69, pp. 1273- 1281 ,(1999) , 10.1093/AJCN/69.6.1273
Oskar Adolfsson, Brigitte T. Huber, Simin Nikbin Meydani, Vitamin E-Enhanced IL-2 Production in Old Mice: Naive But Not Memory T Cells Show Increased Cell Division Cycling and IL-2-Producing Capacity The Journal of Immunology. ,vol. 167, pp. 3809- 3817 ,(2001) , 10.4049/JIMMUNOL.167.7.3809
Melissa G. Marko, Tanvir Ahmed, Stephen C. Bunnell, Dayong Wu, Heekyung Chung, Brigitte T. Huber, Simin Nikbin Meydani, Age-Associated Decline in Effective Immune Synapse Formation of CD4+ T Cells Is Reversed by Vitamin E Supplementation Journal of Immunology. ,vol. 178, pp. 1443- 1449 ,(2007) , 10.4049/JIMMUNOL.178.3.1443