Spontaneous Pneumothorax in Patients With Acquired Immunodeficiency Syndrome Treated With Prophylactic Aerosolized Pentamidine

摘要: • Spontaneous pneumothorax is a known complication of Pneumocystis carinii pneumonia in patients with the acquired Immunodeficiency syndrome. To evaluate possible pathogenesis and natural history receiving aerosolized pentamidine prophylaxis, we retrospectively reviewed 327 outpatients positive for human immunodeficiency virus pentamidine. There were 12 spontaneous pneumothoraces this group patients. Seventy-five percent had roentgenographic evidence fibrocystic lung parenchyma clinical active pneumonia. The majority (83%) required chest tube evacuation. was 50% mortality rate associated complication. These findings suggest that treated most commonly represents prophylaxis failure high rate. ( Arch Intern Med . 1990;150:2167-2168)