Beneficial effect of phosphatidylcholine supplementation in alleviation of hypomania and insomnia in a Chinese bipolar hypomanic boy and a possible explanation to the effect at the genetic level.
作者： Shitao Rao , Marco HB Lam , Yun Kwok Wing , Larina CL Yim , Winnie CW Chu
DOI: 10.1186/S40064-015-1002-Y
关键词:
摘要: Introduction Recent studies indicated that supplementation of phosphatidylcholine has been found to be beneficial for psychiatric diseases and Diacylglycerol Kinase, Eta (DGKH) protein was involved in regulating the metabolism phosphatidic acid diacylglycerol. This study reported a case 16-year-old Chinese boy with bipolar hypomania symptoms receiving phosphatidylcholine, genetic risk variant DGKH gene performed an attempt provide explanation potential effect supplementation.
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Alan R. Hirsch, Use of lecithin to restore olfaction and taste ,(1989)
John H. Growdon, Richard J. Wurtman, Process and composition for treating disorders by administering lecithin ,(1979)
Robert L. Spitzer, User's guide for the Structured clinical interview for DSM-III-R : SCID American Psychiatric Association. ,(1990)
Deepak C D'souza, Rajiv Radhakrishnan, Edward Perry, Savita Bhakta, Nagendra M Singh, Richa Yadav, Danielle Abi-Saab, Brian Pittman, Santosh K Chaturvedi, Mahendra P Sharma, Morris Bell, Chittaranjan Andrade, None, Feasibility, safety, and efficacy of the combination of D-serine and computerized cognitive retraining in schizophrenia: an international collaborative pilot study. Neuropsychopharmacology. ,vol. 38, pp. 492- 503 ,(2013) , 10.1038/NPP.2012.208
Frank Dudbridge, A note on permutation tests in multistage association scans. American Journal of Human Genetics. ,vol. 78, pp. 1094- 1095 ,(2006) , 10.1086/504527
Frank Dudbridge, Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Human Heredity. ,vol. 66, pp. 87- 98 ,(2008) , 10.1159/000119108
Michael John Berridge, Inositol Trisphosphate, Calcium, Lithium, and Cell Signaling JAMA: The Journal of the American Medical Association. ,vol. 262, pp. 1834- 1841 ,(1989) , 10.1001/JAMA.1989.03430130110043
Jian-jun Chen, Hua Huang, Li-bo Zhao, De-zhi Zhou, Yong-tao Yang, Peng Zheng, De-yu Yang, Peng He, Jing-jing Zhou, Liang Fang, Peng Xie, Sex-Specific Urinary Biomarkers for Diagnosing Bipolar Disorder PLoS ONE. ,vol. 9, pp. e115221- ,(2014) , 10.1371/JOURNAL.PONE.0115221
Janis E. Wigginton, David J. Cutler, Gonçalo R. Abecasis, A note on exact tests of Hardy-Weinberg equilibrium. American Journal of Human Genetics. ,vol. 76, pp. 887- 893 ,(2005) , 10.1086/429864