The anthelmintic efficacy of the plant, Albizia anthelmintica, against the nematode parasites Haemonchus contortus of sheep and Heligmosomoides polygyrus of mice

摘要: Albizia anthelmintica Brong., belongs to the plant family Mimosaceae. The is widely used in East Africa by poor smallholder farmers and pastoralists treat their livestock against internal parasites. anthelmintic effects of water extracts from bark A. anthelmintica, obtained three different geographic areas Kenya using methods preparation, were tested at doses sheep mice infected with nematode parasites Haemonchus contortus Heligmosomoides polygyrus, respectively. Lambs 3000 infective larvae H. treated preparations 28 days later, while 200 polygyrus 18 later. Proximate analysis established high levels crude proteins bark. Two out 45 suffered transient bloat, which was relieved dosing a surfactant. Significant reductions faecal egg counts observed lambs two experiments undertaken, but efficacy achieved well below 70% reduction required. Similar values packed red cell volume live weight gain for control lambs. There no overall significant effect treatment on total worm mice. A dose rate 1000 mg/kg bodyweight preparation resulted death all results show that not efficacious or