Microreactor Technology as an Efficient Tool for Multicomponent Reactions

作者: Ana Cukalovic , Jean-Christophe M. R. Monbaliu , Christian V. Stevens

DOI: 10.1007/7081_2009_22

关键词:

摘要: Multicomponent reactions are an important tool in organic synthesis as they often allow the circumvention of multistep procedures by combining three or more molecules into one structure a single step. An additional asset approach is significant increase combinatorial possibilities, since modification final product easily accomplished implementing minor changes reaction setup; this obviously allows considerable savings time and resources. These advantages particular interest pharmaceutical research for construction libraries. In order to sustainability chemical processes, field intensively explored, novel frequently reported. Microreactor technology also offers contemporary way conducting sustainable fashion due miniaturization increased safety, technically improved manner intensified process efficiency. This relatively new implemented applications getting used research. The combination benefits from two approaches clearly presents attractive design, chapter overview reported examples which microreactor multicomponent combined, usually with dramatically results compared those previously

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