The content of cadmium, cobalt and nickel in laryngeal carcinoma

作者: Janusz Klatka , Marek Remer , Ryszard Dobrowolski , Wioletta Pietruszewska , Agnieszka Trojanowska

DOI: 10.5114/AOMS.2011.23422

关键词:

摘要: Introduction The aim of the study was to determine content cadmium (Cd), cobalt (Co) and nickel (Ni) in samples from laryngeal carcinoma comparison with level these elements healthy mucous membrane same larynx. Material methods conducted on 43 patients carcinoma. levels Cd, Co, Ni control tissues determined by inductively coupled plasma optical emission spectrometry (ICP - OES) using sequential spectrometer. Results No significant differences were found between vs without However, it noted that concentration Cd tumors metastases cervical lymph nodes significantly higher than metastases. Co more advanced tumors: stage-T4 stage T3. It is interest rural urban areas. Conclusions imbalance nickel, cancer may be due a changed cellular metabolism process. results our reveal metals areas which suggests this fact related environmental or occupational factors therefore requires further study.

参考文章(26)
Hopfer Sm, Sunderman Fw, Mitchell Jm, Allpass Pr, Maenza Rm, Damjanov I, Induction of renal cancers in rats by intrarenal injection of nickel subsulfide. Journal of environmental pathology and toxicology. ,vol. 2, pp. 1511- ,(1979)
TNM classification of malignant tumours Published in <b>2010</b> in Chichester, West Sussex, UK ;Hoboken, NJ by Wiley-Blackwell. ,(1987) , 10.1007/978-3-642-82982-6
Einar Pedersen, Arne Chr. Høgetveit, Aage Andersen, Cancer of respiratory organs among workers at a nickel refinery in Norway. International Journal of Cancer. ,vol. 12, pp. 32- 41 ,(1973) , 10.1002/IJC.2910120104
J Olsen, S Sabroe, Occupational causes of laryngeal cancer. Journal of Epidemiology & Community Health. ,vol. 38, pp. 117- 121 ,(1984) , 10.1136/JECH.38.2.117
T Sorahan, Lung cancer mortality in UK nickel-cadmium battery workers, 1947-2000. Occupational and Environmental Medicine. ,vol. 61, pp. 108- 116 ,(2004) , 10.1136/OEM.2003.009282
N. Gault, C. Sandre, J.-L. Poncy, C. Moulin, J.-L. Lefaix, C. Bresson, Cobalt toxicity: chemical and radiological combined effects on HaCaT keratinocyte cell line. Toxicology in Vitro. ,vol. 24, pp. 92- 98 ,(2010) , 10.1016/J.TIV.2009.08.027
C G Elinder, T Kjellstrom, C Hogstedt, K Andersson, G Spang, Cancer mortality of cadmium workers. Occupational and Environmental Medicine. ,vol. 42, pp. 651- 655 ,(1985) , 10.1136/OEM.42.10.651
Paola Collecchi, Mauro Esposito, Silvio Brera, Enzo Mora, Ambrogio Mazzucotelli, Massimo Oddone, The distribution of arsenic and cobalt in patients with laryngeal carcinoma Journal of Applied Toxicology. ,vol. 6, pp. 287- 289 ,(1986) , 10.1002/JAT.2550060410
R Doll, L G Morgan, F E Speizer, Cancers of the Lung and Nasal Sinuses in Nickel Workers British Journal of Cancer. ,vol. 24, pp. 623- 632 ,(1970) , 10.1038/BJC.1970.76
İ. Durak, M. Kavutcu, O. Canbolat, A. Ü. Işik, Ö. Akyol, Concentrations of some major and minor elements in larynx tissues with and without cancer Biometals. ,vol. 7, pp. 45- 48 ,(1994) , 10.1007/BF00205193