Notch signaling and the developing skin epidermis.
作者： Daniela Massi , John Panelos
DOI: 10.1007/978-1-4614-0899-4_10
关键词:
摘要: The innermost (basal) layer of the skin epidermis consists proliferative progenitors which give rise to multiple differentiating layers providing a barrier that keeps inside body moist and protects from outside assaults by physical, environmental biological factors. is maintained throughout life through proliferation stem cells differentiation their progeny. Notch signaling pathway highly conserved molecular network plays an essential role in cell fate determination during embryogenesis also postnatal life. Data ongoing studies indicate orchestrates process epidermal sequential activity different ligands, receptors downstream pathways.
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