The effects of drugs on cough.

摘要: The pharmacologic treatment of cough can be divided into two main categories: therapy with controls, prevents or eliminates (i.e., antitussive) and that makes more effective pro-tussive). Definitive antitussive depends on determining the aetiology operant pathophysiologic mechanism then initiating specific treatment; it almost uniformly successful. Non-specific is directed at symptom; indicated when definitive cannot given. For pathologic in man, predominantly studied patients chronic bronchitis, following non-specific drugs have been shown to effective: aerosolized ipratropium bromide, all narcotics phenanthrene alkaloid group (e.g., morphine codeine), non-narcotics, dextromethorphan, glaucine, diphenhydramine, caramiphen, viminol diviminol. Although studies hypertonic saline aerosol improve clearance, there are no data, date, convincingly demonstrated this agent any other pro-tussive drug clinically useful.